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The Spokesman-Review Newspaper
Spokane, Washington  Est. May 19, 1883

Smoker’s Face Smoking Damages Cells And Tissues, Having Myriad Effects On The Body

Jane E. Brody New York Times

The doctor could tell the patient had once been an attractive woman.

But now, though only in her 50s, her face was etched with wrinkles, her features gaunt-looking with prominent underlying bones and her skin shriveled and gray with purplish blotches.

Diagnosis: smoker’s face.

Dr. Douglas Model of Eastbourne, England, added this condition to the medical lexicon in 1985 after surveying 116 patients and correctly identifying roughly half of current smokers by their facial features alone.

The distinctive characteristics of smoker’s face, which makes people look far older than their years, were present in 19 (46 percent) current smokers, three (8 percent) former smokers and no nonsmokers, irrespective of their age, social class, recent weight fluctuations and exposure to sunlight.

To illustrate his point, he included photographs of some famous and nonfamous smokers and nonsmokers, including the dramatically wrinkled face of the poet W.H. Auden.

Dr. Jeffrey B. Smith, a senior resident in dermatology at the University of South Florida in Tampa, recalled this poignant diagnosis in a review of the effects of smoking on the skin published in June in the journal Dermatology. He studied 311 reports of smoking-related skin conditions.

Perhaps, he hopes, the all-too-visible and often discomforting damage to skin induced by smoking will encourage more people to quit, “especially those who may be more concerned about their outward appearance than the potential internal damage associated with smoking.”

Smoking damages cells and tissues in so many ways that it can have myriad effects on the body. Among them are these:

Wrinkles: “For some patients the threat of wrinkles may be a more powerful motivator to help them stop smoking than the more deadly consequences of smoking,” Smith wrote. He explained that, as with skin that is overexposed to sunlight, smoking causes thickening and fragmentation of elastin, the elastic fibers that are long and smooth in healthy skin.

Smoking also depletes the skin’s oxygen supply by reducing circulation. It decreases the formation of collagen, the skin’s main structural component, and may reduce the water content of the skin, all of which increase wrinkling. Smoking also interferes with the skin’s ability to protect itself against damage by free radicals, highly reactive substances that are omnipresent in tobacco smoke. In women, smoking diminishes the level of circulating estrogen, which in turn fosters dryness and disintegration of skin tissues.

Skin cancers: Two kinds of skin cancers, the more curable squamous cell carcinomas and the often lethal melanomas, are influenced by smoking. Smith said that although smoking did not cause melanoma, smokers with melanoma were more likely to die of their disease. They are twice as likely to have advanced disease at the time of diagnosis and are more likely to have their cancers spread within two years of diagnosis, probably because smoking impairs the immune system.

As for squamous cell carcinoma, even when exposure to sunlight was taken into account, smokers were found to be at greater risk of developing this cancer.

Other cancers: Cancers of the lip, mouth, penis, anus and vulva are also more common in smokers than nonsmokers. For example, in one study of 903 female cancer patients, 60 percent of those with vulvar and anal cancers and 42 percent of those with cervical and vaginal cancers were smokers as against only 27 percent of comparable women without cancer. Smoking more than 10 cigarettes a day more than doubles a man’s risk of developing penile cancer.

Delayed wound healing: The problem of slow or incomplete healing of wounds associated with exposure to cigarette smoke was clearly demonstrated in laboratory animals in the 1970s. Then surgeons began reporting on similar problems in patients who smoked: larger scars in women undergoing exploratory abdominal surgery, more complications and skin sloughing after face lifts and a much higher failure rate of skin grafts, for example. The more and the longer patients had smoked, the greater the likelihood of impaired wound healing.

Psoriasis: Studies of both men and women with this unsightly and discomforting skin condition have shown that smokers are about two to three times as likely to develop it as nonsmokers. And the more cigarettes smoked, the greater the risk.

Oral lesions: In addition to smoker’s face, there is also smoker’s palate and smoker’s tongue. The tars and heat of tobacco smoke can cause tiny red pimples in the mouth that result from an inflammation of the openings of salivary glands. Smokers also often develop depressions on the surface of the tongue. Potentially more serious, however, are lesions called leukoplakia, which are about six times more common in smokers than in nonsmokers. Although benign, these white patches in the mouth can become cancerous.

Buerger’s disease: This blood vessel disease results in poor circulation in the lower legs, causing skin problems like burning, tingling and ulcerations. “It usually occurs in young men who smoke, men in their 30s,” Smith said. “But now that women are smoking a lot more, we’re seeing it in women, too.”